Programme by topic
Please select the topic below to view the sessions within that theme.
Neurons and glia: intrinsic properties, cell biology and cell types
Synapses and plasticity
Neurodevelopment, stem cells, and associated disorders
Sensory and motor systems
Circuit dynamics and oscillations
Cognition and behaviour
Computational and theoretical neuroscience
Psychiatry and mental health
Ageing and dementia
Parkinson's disease and other neurodegenerative disorders - FESTIVAL PARTNER PARKINSON'S UK TOPIC
Other neurological disorders
Treatments and translational neuroscience
Methods and technology development
Other (e.g. History, teaching, outreach, etc)
Neurons and glia: intrinsic properties, cell biology and cell types
Wednesday 26th April 2023, 09:30 - 11:10 BST
Live imaging in the CNS: new insights on oligodendrocyte form, function and plasticity
- Daniel Fulton, University of Birmingham, UK: Live-imaging of oligodendrocyte myelination and plasticity in forebrain slice cultures (co-chair)
- Cody Call, Oregon Health and Science University, USA: Paranodal bridges link chains of myelin sheaths that are vulnerable to age-related degeneration (co-chair)
- Julia Edgar, University of Glasgow, UK: Live imaging cargoes in myelin’s highway to the axon
- Jenea Bin, University of Edinburgh, UK: Live-imaging Myelinated Axon Development in Zebrafish
Synapses and plasticity
Sunday 23rd April 2023, 12:00 - 14:40 BST
Synaptic neurodevelopmental disorders: genes, cells, circuits, cognition
- Kate Baker, MRC Cognition and Brain Sciences Unit, University of Cambridge (non-speaking co-chair)
- Asma Soltani, Department of Physiology, Neuroscience and Development, University of Cambridge, UK: Inhibitory interneurons and network development in MECP2 deficiency (co-chair)
- Sarah Gordon, Florey Institute of Neuroscience and Mental Health, UK: Unravelling the pathogenicity of SYT1-associated neurodevelopmental disorder
- Cezar Tigaret, Neuroscience & Mental Health Research Institute, Cardiff University, UK: CACNA1C, synaptic plasticity and contextual learning in psychiatric disorders
- Susana Ribeiro dos Louros, University of Edinburgh, UK: Excessive proteostasis contributes to pathology in Fragile X Syndrome
Neurodevelopment, stem cells, and associated disorders
Sunday 23rd April 2023, 12:00 - 14:40 BST
Biological mechanisms underlying neurodevelopmental and neuropsychiatric disorders: findings from hPSC models
- Eunju Jenny Shin, Keele University, UK: Understanding genetic risk factors for neuropsychiatric disorders in cortical interneuron development using human pluripotent stem cell differentiation (co-chair)
- Deepak Srivastava, King's College London, UK: talk title TBC
- In-Hyun Park, Yale University, USA: talk title TBC
- Rana Fetit, University of Edinburgh, UK: The effects of 16p11.2 deletion on subpallial development in ventral telencephalic organoids (co-chair)
Tuesday 25th April 2023, 09:30 - 11:10 BST
Malformations of the central nervous system in Ciliopathies
- Sylvie Schneider Maunoury, Institut de Biologie Paris Seine (IBPS) , Sorbonne University, France: An organoid approach of neurodevelopmental defects in neural ciliopathies
- Vasanta Subramanian, University of Bath, UK: Role of the basal body protein Talpid3 in Brain Development-implications for Joubert syndrome (co-chair)
- Raman Das, Faculty of Life Sciences, University of Manchester, UK: Dynamic modulation of the cell signalling response by primary cilium remodelling during vertebrate neuronal differentiation (co-chair)
- Colin Johnson, Faculty of Biological Sciences, University of Leeds, UK: Neurodevelopmental defects in severe ciliopathies: insights from gene discovery and functional genomics
Sensory and motor systems
Sunday 23rd April 2023, 10:20 - 12:00 BST
Neuromodulation enhanced activity-based therapy for motor recovery following Spinal Cord Injury
- Chloe Shin-Yi Chiou, University of Birmingham, UK: Pairing movements across arms and the trunk for enhancing motor output of the trunk after spinal cord injury (co-chair)
- Ronaldo Ichiyama, University of Leeds, UK: Neuromodulation of Spinal Circuits: Neurorehabiliation and Recovery of Function Following Severe SCI
- Lynsey Duffell, the University College London: First UK experience of epidural Spinal Cord Stimulation in a patient with motor complete spinal cord injury – motor recovery and multisystem gains (co-chair)
- Joseph Steel, the London Spinal Cord Injury Unit at the Royal National Orthopaedic Hospital: Early application of neuromodulation to enhance recovery following Spinal Cord Injury - a clinical perspective
Monday 24th April 2023, 15:30 - 17:10 BST
Short ride in a fast sense: hearing from hair cells to cortex
- Corné Kros, University of Sussex, UK: Mechano-electrical transducer channel pore properties vary with frequency position along the cochlea (co-chair)
- Snezana Levic, Brighton and Sussex Medical School, UK: The role of the calcium-sensing receptor in regulating intracellular calcium dynamics in the mammalian cochlea (co-chair)
- Victoria Ciampani, University of Leicester, UK: Kv3 channel modulation of action potentials at high frequencies in the auditory brainstem
- Andrew King, Oxford University, UK: Why do we need an auditory cortex?
Circuit dynamics and oscillations
Sunday 23rd April 2023, 12:00 - 14:40 BST
Circadian Neuroscience. Full information
- Rob Lucas, Universtiy of Manchester, UK: The importance of daytime light for circadian health (co-chair)
- Aarti Jagannath, University of Oxford, UK: The role of Salt-Inducible Kinases in regulating sleep and circadian rhythms
- Marco Brancaccio, Imperial university, UK: Glial control of circadian rhythms in the suprachiasmatic nucleus
- Lukasz Chrobok, University of Bristol, UK: Ticking and talking in the brainstem: circadian timekeeping properties of the dorsal vagal complex (co-chair)
Cognition and behaviour
Sunday 23rd April 2023, 16:20 - 18:00 BST
What do human hippocampal neurons code? Full information
Session convened by the British Association of Cognitive Neuroscience.
- Luca Kolibius, University of Glasgow, UK: Hippocampal neurons code individual episodic memories in humans (co-chair)
- Rodrigo Quian Quiroga, University of Leicester, UK: Concept neurons as the building blocks of declarative memory (co-chair)
- Doris Dijksterhuis, Netherlands Institute for Neuroscience, UK: Pronouns reactive concept cells in the human medial temporal lobe
- Robert Mok, University of Cambridge, UK: How the hippocampus encodes concept and spatial representations: a multi-level account from behaviour to neurons
Tuesday 25th April 2023, 09:30 - 11:10 BST
Behavioural insights into the nature of spatial memory: Full information
Session convened by European Brain and Behaviour Society
- Alexander Easton, Durham University, UK: non-speaking co-chair
- Dorothy Tse, Edge Hill University, UK: non-speaking co-chair
- Steven Poulter, Durham University, UK: Remembering where things are: Vector Trace cells, Theta Oscillations and Virtual Reality
- Eleonore Duvelle, Dartmouth University, USA: Hippocampal place cell firing during flexible spatial navigation
- Lisa Genzel, Radboud University, Netherlands: The HexMaze: testing previous knowledge effects in map learning
- Jan Wiener, Bournemouth University, UK: Route sequence knowledge aids the formation of cognitive graphs
Tuesday 25th April 2023, 15:30 - 17:10 BST
Aversive cognition and pain: from theory to neuroengineering. Full information
- Dounia Mulders, Universite' Catholique de Louvain, Belgium: Inference and control of aversive states in the human brain
- Ariane Delgado-Sanchez, University of Manchester, UK: Pain phenotyping using Bayesian modelling (co-chair)
- Christopher Brown, University of Liverpool, UK: Joint modelling of priming, perceptual and aversive learning within a Bayesian framework
- Ben Seymour, University of Oxford, UK: Neuroengineering for chronic pain
Computational and theoretical neuroscience
Wednesday 26th April 2023, 09:30 - 11:10 BST
Recent advances at the interface of biological intelligence and deep neural networks. Full information
- Srikanth Ramaswamy, Newcastle University, UK: Multi-scale principles of neuromodulatory systems in neural networks: now and beyond
- Maija Filipovica, University of Bristol, UK: AI-driven Cholinergic theory of learning and cognitive robustness
- Randy Bruno, University of Oxford, UK: Cortical Layers in Context and Learning
- Sylvia Schroeder, University of Sussex, UK: How adaptable are the first stages of visual processing?
Psychiatry and mental health
Sunday 23rd April 12:00 – 14:40 BST
The truth about drugs: the neuroscience, evidence, and drug checking.
Session convened by Drug Science
- Hannah Thurgur, Drug Science, UK: Feasibility study of medical cannabis for the treatment of Long COVID symptoms (co-chair)
- David Nutt, Imperial College London, UK: Between Receptor and Mind: How Psychedelics Work in the Brain
- Anne Schlag, Kings College London, UK: Real World Evidence on the effectiveness of Cannabis-based medicinal products (CBMPs) (co-chair)
- Fiona Measham, University of Liverpool, UK: Introducing the UK's first Home Office-licensed, local government-funded regular drug checking service
Sunday 23rd April 16:20 – 18:00 BST
Genetic, epigenetic and immune mechanisms for major psychiatric disorders
- Ed Bullmore, University of Cambridge (co-chair)
- Andrew McIntosh, University of Edinburgh: Recent insights in depression from genetics and multi-omic studies
- Marion Leboyer, INSERM: Immuno-genetics towards precision psychiatry
- Mary-Ellen Lynall, University of Cambridge (co-chair): Innate and adaptive cellular immunology in psychiatry: insights from genetic association studies
- Jonathan Mill, University of Exeter; Regulatory genomic pathways to neuropsychiatric illness
Monday 24th April 2023, 09:30 - 11:10 BST
HIV mental health: where are we headed?
Supported by the Collaborative Initiative for Paediatric HIV Education and Research by the International AIDS Society
- Arish Mudra Rakshasa-Loots, The University of Edinburgh, UK (co-chair): Is it "all in your head"? The contribution of neuroinflammation to depression in a South African cohort of adolescents with and without HIV
- Etheldreda Nakimuli-Mpungu, Makerere University, UK: Long-term effect of group support psychotherapy on depression and HIV treatment outcomes: Secondary analysis of a cluster randomized trial in Uganda
- Kate Alford, Brighton & Sussex Medical School, UK: Quality of life in people living with HIV with cognitive impairment
- Mercy Shibemba, PENTA Foundation, UK (co-chair): 'Everything makes sense now!' The importance of sharing research with children and young people
Monday 24th April 2023, 09:30 - 11:10 BST
WORKSHOP: Impactful hypotheses in translational psychiatric neuroscience: a critical appraisal
- Alan Palmer, Elixa MediScience, UK: (co-chair)
- Ekta Patel, The Psychiatry Consortium, UK: (co-chair)
- Robin Murray, King's College London, UK: The dopamine hypothesis of schizophrenia
- Rachel Gurrell, Noema Pharma, UK: The GABAA receptor hypothesis of anxiety
- Phil Cowen, Oxford University, UK: The serotonin hypothesis of depression
- David Nutt, Drug Science, UK: The dysregulated brain circuit hypothesis of conditions associated with impaired mental health: the pivotal role for psychedelic drugs
Monday 24th April 2023 17:10 - 18:10 BST
PLENARY: Neuroscience and Neurodiversity
Sue Fletcher-Watson, University of Edinburgh, UK with
Mary Doherty, Brighton & Sussex Medical School/ Our Lady’s Hospital, Ireland
18:30 BST Tuesday 25th April
When It Is Darkest: Understanding the psychology of suicide risk
Public lecture by Professor Rory O'Connor, University of Glasgow
Ageing and dementia
Sunday 23rd April 2023, 10:20 - 12:00 BST
Immunotherapy in neurodegenerative diseases: Full information.
Convened by the British Neuropathological Society
- James Nicoll, Southampton General Hospital, UK: Pathology of immunotherapy in dementias
- Chenxi Qiu, Harvard Medical School, USA: Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice
- Jean-Cosme Dodart, Vaxxinity, USA: The UBITh platform in neurodegenerative diseases
- Nivedita Agarwal, IRCCS Eugenio Medea, Italy: Amyloid Related Imaging Abnormalities after immunotherapy
Sunday 23rd April 2023, 12:00 - 14:40 BST
Glia in neurodegeneration: genetics, mechanisms and therapeutic targets. Full information
- Peter St George-Hyslop, University of Cambridge, UK: Microglia mechanisms to counteract amyloid pathology
- Julia TCW, Boston University School of Medicine, USA: Deciphering functional mechanisms of Alzheimer's disease (AD) genetic risk in iPSC models
- Hazel Hall-Roberts, UK Dementia Research Institute at Cardiff, UK: Modelling Alzheimer’s disease polygenic risk in iPSC-microglia-like cells (co-chair)
- Emma Mead, Alzheimer's Research UK Oxford Drug Discovery Institute, UK: Glial therapeutic targets for neurodegenerative disease (co-chair)
Monday 24th April 2023, 09:30 - 11:10 BST
Neurovascular contributions to dementia: Full information
Session convened by The Physiological Society
- Silvia Anderle, University of Sussex, UK: APOE genotype and amyloid-β interactions in the emergence of AD pathology (co-chair)
- Beth Eyre, University of Sheffield, UK: Investigating the effects of atherosclerosis in an Alzheimer's disease model (co-chair)
- Axel Montagne, University of Edinburgh, UK: Loss of Endothelial-Pericyte Crosstalk: A Major Driving Force in Dementia Pathology
- Edith Hamel, McGill University, Canada: Brain endothelial cell dysfunction, white matter alterations and cognitive deficits
Parkinson's disease and other neurodegenerative disorders
Sunday 23rd April 2023, 10:20 - 12:00 BST
Mitochondrial dysfunction and therapeutic potential
Session convened by Parkinson’s UK
- Niamh Connolly, Royal College of Surgeon Dublin, Ireland: Mitochondrial bioenergetics, dynamics, morphology and stress response in neurons exposed to alpha-synuclein preformed fibrils (co-chair)
- Olga Corti, Paris Brain Institute (Institut du Cerveau), Paris: Mitochondrial dysfunction in the alpha-synuclein preformed fibril mouse model of Parkinson’s disease
- Miratul Muqit, MRC Protein phosphorylation and ubiquitylation unit, Dundee: Decoding Mitochondrial Damage Response Pathways linked to Parkinson’s disease (co-chair)
- Heather Mortiboys, SiTRaN at the University of Sheffield, UK: Targeting mitochondria for disease modification in Parkinson's Disease
Sunday 23rd April 2023, 10:20 - 12:00 BST
Current topics in Neuropsychiatry
Convened by the British Neuropsychiatry Association
- Wendy Phillips, Addenbrooke’s Hospital, Cambridge and Princess Alexandra Hospital, UK: Clinical presentation of synucleinopathies (co-chair)
- Boyd Ghosh, University Hospital Southampton,UK: The clinical presentations of tauopathies (co-chair)
- Thomas Pollak, King’s College London, UK: Autoimmune psychosis: towards improved diagnosis and treatment
- Jeremy Isaacs, St George's University Hospitals NHS Foundation Trust, UK: New insights into functional cognitive disorder
Monday 24th April 2023, 09:30 - 11:10 BST
Dissecting the signaling pathways in Parkinson's and their therapeutic potential
Session convened by Parkinson's UK
- Claudia Manzoni, UCL School of Pharmacy, UK: Modelling the function of LRRK2 as controller of multiple pathways - a systems biology perspective
- Dario Alessi, University of Dundee, UK: Pharmacological strategies targeting LRRK2
- Matthew Gegg, University College London, UK: The effect of glucocerebrosidase deficiency on the endolysosomal pathway and identification of potential pharmacological treatments (co-chair)
- Michela Deleidi, German Centre for Neurodegenerative Diseases (DZNE), Germany: Dissecting GBA1 Parkinson' s disease: from 2D to 3D iPSC models
Monday 24th April 2023, 15:30 - 17:10 BST
Are peripheral and CNS inflammation drivers of neurodegeneration?
Session convened by Parkinson's UK.
- Deborah Kronenberg- Versteeg, University of Tubingen, Germany: New models to investigate the role of microglia in Parkinson’s disease
- Ian Harrison, University College London, UK: Exploring the therapeutic potential of the glymphatic system in the clearance of pathological alpha-synuclein from the brain (co-chair)
- Soyon Hong, University College London, UK: Neuroimmune mechanisms along the gut-brain axis in synucleinopathy models
- Caroline Williams-Gray, Cambridge University, UK: The peripheral immune system: a new therapeutic target in Parkinson's disease (co-chair)
Tuesday 25th April 2023, 09:30 - 11:10 BST
Understanding neurodegeneration through single cell- and organoid-based approaches
Session convened by CURE-ND
- Giles Hardingham, UK Dementia Research Institute at The University of Edinburgh, UK: Glia-neuronal interactions in Alzheimer's disease (co-chair)
- Wei-Ting Chen, VIB - KU Leuven Center for Brain and Disease Research, Belgium: Exploiting spatial transcriptomics to understand Alzheimer's disease (co-chair)
- Benjamin Galet, Paris Brain Institute, France: Lineage-specific molecular profiling in organoid models of Alzheimer's Disease
- Michela Deleidi, German Centre for Neurodegenerative Diseases (DZNE), Germany: Glucocerebrosidase and Brain Disease: Novel Functions Beyond the Lysosome
Tuesday 25th April 2023, 09:30 - 11:10 BST
Techniques/Technologies driving a better understanding of disease mechanisms
Session convened by Parkinson's UK
- Caleb Webber, University of Cardiff, UK: Exploiting stem cell model heterogeneity with single cell RNAseq (co-chair)
- Tiago Outeiro, Newcastle University, UK: Extracellular vesicles: from basic biology to biomarkers
- Amanda Lewis, École polytechnique fédérale de Lausanne, Switzerland: Insights into alpha-Synuclein accumulation in human brain using correlative light and electron microscopy
- Nora Bengoa-Vergniory, Achucarro Basque Center for Neuroscience, Spain: Visualizing and tackling alpha-synuclein aggregation in Parkinson’s disease therapeutics (co-chair)
Wednesday 26th April 2023, 09:30 - 11:10 BST
Synaptopathy in ALS/FTD
- Chris Henstridge, University of Dundee, UK: Synaptic proteomics reveal molecular signatures of cognitive decline and C9ORF72 in human ALS (co-chair)
- Matthew Livesey, University of Sheffield, UK: Understanding neurophysiological dysfunction in ALS-FTD
- Sara Tacconelli, King's College London, UK: Identifying synaptic interactors of FUS (co-chair)
- Chantelle Sephton, Université Laval, Canada: Understanding early pathological changes in neuromorphology and synapses in ALS/FTD
Other neurological disorders
Sunday 23rd April 2023, 16:20 - 18:00 BST
Neurological effects of COVID-19: Full information
Session convened by the Guarantors of Brain
- Avindra Nath, NIH, Bethesda, USA: Neurological disorders in COVID-19: potential mechanisms of disease (co-chair)
- Michael Lunn, UCL, London, UK: Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome
- Marcel Woo, University Medical Center, Hamburg-Eppendorf, Germany: Cognitive deficits after recovery from COVID-19
- Sijia Zhao, University of Oxford, UK: Rapid vigilance and episodic memory decrements in COVID-19 survivors (co-chair)
Sunday 23rd April 2023, 16:20 - 18:00 BST
Stroke and neuroprotection: novel strategies: Full information
Session convened by Neuroscience Ireland
- Karen Doyle, National University of Ireland, Galway, Ireland: Stroke as a systemic disease: understanding the clots that cause strokes (co-chair)
- Christian Waeber, University College Cork, Ireland: The Role of Regulatory T Cells in Stroke Recovery
- Malcolm MacLeod, University of Edinburgh, UK: Improving the translational impact of preclinical stroke research
- Johanna Ospel, University of Basel, Switzerland: Current state-of-the-art acute ischemic stroke treatment from a clinician's perspective (co-chair)
Tuesday 25th April 2023, 09:30 - 11:10 BST
Innovations in research from Epilepsy Research UK: Full information
Session convened by Epilepsy Research UK
- Gareth Morris, University College London, UK: MicroRNA-based therapies for epilepsy (co-chair)
- Faye McLeod, Newcastle University, UK: Modelling monogenic epilepsy in human brain slice cultures (co-chair)
- Marie Pronot, University of Edinburgh, UK: Pathophysiological consequences of middle domain DNM1 mutations
- Fourth speaker to be added
Tuesday 25th April 2023, 15:30 - 17:10 BST
Glial function in CNS disorders: are astrocytes the real stars? Full information
- Veronique Miron, University of Edinburgh, UK: Astrocyte-oligodendrocyte interaction regulates central nervous system remyelination
- Matthew Broadhead, University of St Andrews, UK: Selective Vulnerability of Tripartite Synapses in Amyotrophic Lateral Sclerosis (co-chair)
- Disha Shah, Katholieke Universiteit Leuven, Belgium: Astrocytic calcium dysfunction at the early stages of Alzheimer's Disease
- Trevor Bushell, University of Strathclyde, UK: Astrocytes and major depressive disorder: a target for novel treatments? (co-chair)
Wednesday 26th April 2023, 09:30 - 11:10 BST
Ion channelopathies in neurodevelopmental disorders: Full information
Session convened by Société des Neurosciences /British Neuroscience Association
- Shehrazade Dahimene, University College London, UK: How a point mutation in CACNA2D1, encoding the calcium channel auxiliary subunit α2δ-1, contributes to early-onset developmental epileptic encephalopathy
- Philippe Lory, Institut de Génomique Fonctionnelle, France: Gain-of-Function mutations in calcium channel genes are an emerging cause of severe neurodevelopmental disorders
- Florence Riccardi, Centre de Génétique Médicale de Marseille, France: RNA interference-based therapeutic development for KCNQ2-related epileptic and developmental encephalopathies (co-chair)
- Andrew Penn, University of Sussex, UK: Synaptic dysfunction associated with mutations in GRIN2B: Influence of subunit composition and mutant classification
Treatments and translational neuroscience
Sunday 23rd April 2023, 12:00 - 14:40 BST
The truth about drugs: the neuroscience, evidence, and drug checking
Session convened by Drug Science
- Hannah Thurgur, Drug Science, UK: Feasibility study of medical cannabis for the treatment of Long COVID symptoms (co-chair)
- David Nutt, Imperial College London, UK: Between Receptor and Mind: How Psychedelics Work in the Brain
- Anne Schlag, Kings College London, UK: Real World Evidence on the effectiveness of Cannabis-based medicinal products (CBMPs) for neurological conditions (co-chair)
- Fiona Measham, University of Liverpool, UK: Introducing the UK's first Home Office-licensed, local government-funded regular drug checking service
Sunday 23rd April 2023, 16:20 - 18:00 BST
UK MND Research Institute: Translating into treatment for MND - is the time now?
Session convened by MND Scotland, MND Association and My Name’5 Doddie Foundation
- Ammar Al-Chalabi, King's College London, UK: The challenges of motor neuron disease research and the opportunities ahead (co-chair)
- Arpan Mehta, University of Edinburgh and UCL, UK: MND-SMART - delivering innovation in clinical trials from bench to bedside (co-chair)
- Pamela Shaw, University of Sheffield, UK: Translational pipeline of potential neuroprotective therapies and biomarkers
- Alex Thompson, University of Oxford, UK: Identifying early ‘presymptomatic’ disease markers
Monday 24th April 2023, 09:30 - 11:10 BST
Brain and muscle channelopathies: from bench to bedside
- Emma Matthews, St George's University of London, UK: Muscle channelopathies: unexpected clinical phenotypes and what they teach us about other paroxysmal neurological disorders
- Andreas Brunklaus, Royal Hospital for Children, Glasgow and Glasgow University, UK: Gene variant effects across sodium channelopathies predict function and guide precision therapy
- Stephanie Schorge, University College London, UK: Harnessing mechanistic insights from channelopathies to develop gene therapies for non-genetic epilepsies (co-chair)
- Karen Suetterlin, Newcastle University, UK: Bridging the preclinical-clinical gap: reverse translation of muscle velocity recovery cycles allows in vivo assessment of skeletal muscle excitability in mice and humans (co-chair)
Monday 24th April 2023, 15:30 - 17:10 BST
Developments in translational biology
Session convened by Alzheimer’s Research UK
- David Rubinsztein, University of Cambridge, UK: Autophagy, a guardian against neurodegeneration
- Giedre Cepukaityte, University College London, UK: Early detection of neurodegenerative diseases using digital technologies (co-chair)
- Victor Perez, Exscientia, UK: NLRP3: AI structure-based drug discovery guided optimisation of phenotypic hits towards a clinical candidate
- Inma Rioja, Bicycle Therapeutics, UK: Bicyclic peptides (Bicycles) as novel multipurpose delivery systems
Monday 24th April 2023, 15:30 - 17:10 BST
Advances in fundamental and clinical neurosciences
Session convened by the Guarantors of Brain.
- Britta Eickholt, Charite, Berlin, Germany: Cell signalling and its implications for brain disorders (co-chair)
- Sam Olum, Gulu University, Uganda: Clinical features of nodding syndrome
- Charlie Arber, University College London, UK: Induced pluripotent stem cell models of Alzheimer’s disease (co-chair)
- Sarosh Irani, Oxford, UK: Insights into how autoantibodies are made and cause disease in the CNS
Tuesday 25th April 2023, 15:30 - 17:10 BST
Novel strategies to improve drug delivery to the CNS, for treatment of psychiatric and neurodegenerative diseases
Session convened by the British Association for Psychopharmacology
- Khuloud Al-Jamal, King's College London, UK: Quantitative and qualitative analyses of gold nanorods distribution in the brain following nose to brain administration
- Omar Mokrane, University College London, UK: Delivery of CRISPR-Cas9 to the Brain for the Treatment of CNS Disease (co-chair)
- Maddy King, University of Nottingham, UK: Use of a novel cell-penetrating peptide to facilitate nose-brain delivery of oxytocin for treatment of psychiatric illness (co-chair)
- David Dickens, University of Liverpool, UK: Strategies to boost the brain delivery of a NMDA receptor antagonist by targeting drug transporters at the blood-brain barrier
Methods and technology development
Sunday 23rd April 2023, 10:20 - 12:00 BST
Brain models to expedite preclinical to clinical translation in neuro-oncology
Session convened by the British Neuro-oncology Society
- Victoria Wykes, University of Birmingham, UK: Development of patient-derived pre-clinical models of brain tumours (co-chair)
- Manav Pathania, University of Cambridge, UK: A Compendium of Syngeneic, Transplantable Paediatric High-Grade Glioma Models Reveals Subtype-Specific Therapeutic Vulnerabilities
- Harish Poptani, University of Liverpool, UK: Neuro-imaging and spectroscopic methods in preclinical models of brain tumours
- Neil Carragher, University of Edinburgh, UK: High content phenotypic profiling across patient derived glioblastoma stem cell models
Monday 24th April 2023, 09:30 - 11:10 BST
Refining the use of head fixation and food & water control in rodents
Session convened by NC3Rs
- Chris Barkus, NC3Rs, UK: NC3Rs working group on high-yield rodent behavioural experiments (co-chair)
- Malamati Bitzidou, The Francis Crick Institute, UK: The head fixation surgery and procedure (co-chair)
- Adil Khan, King's College London, UK: Food restriction for optimizing high-yield behavioural assays
- Emma Robinson, University of Bristol, UK: Habituation methods to improve scientific outcomes and benefit animal welfare
Tuesday 25th April 2023, 09:30 - 11:10 BST
Supercharge your brain research workflow: whole organ to single cells (Full information)
Session convened by Miltenyi Biotec
- Jill Fowler, Centre for Discovery Brain Sciences, University of Edinburgh, UK: Investigating global disease-associated glial cell changes in the chronic response to focal cerebral ischaemia with single cell sequencing
- Iben Lundgaard, Lund University, Sweden: Shedding light on brain clearance
- Kirsty Craigie, Simons Initiative for the Developing Brain, University of Edinburgh, UK: Tissue clearing and light-sheet microscopy to map brain-wide neuronal activation in 3D
- Csaba Adori, Karolinska Institutet, Sweden: Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging
Tuesday 25th April 2023, 09:30 - 11:10 BST
Techniques/Technologies driving a better understanding of disease mechanisms
Session convened by Parkinson's UK
- Caleb Webber, University of Cardiff, UK: Exploiting stem cell model heterogeneity with single cell RNAseq (co-chair)
- Tiago Outeiro, Newcastle University, UK: Extracellular vesicles: from basic biology to biomarkers
- Amanda Lewis, École polytechnique fédérale de Lausanne, Switzerland: Insights into alpha-Synuclein accumulation in human brain using correlative light and electron microscopy
- Nora Bengoa-Vergniory, Achucarro Basque Center for Neuroscience, Spain: Visualizing and tackling alpha-synuclein aggregation in Parkinson’s disease therapeutics (co-chair)
Tuesday 25th April 2023, 15:30 - 17:10 BST
Obtaining and using living human brain tissue for translational research - hype, hope or hassle? (WORKSHOP)
Session convened by the Society of British Neurological Surgeons
- William (Liam) Gray, Cardiff University and University Hospital Wales, UK: Workshop Overview AND Using Primary Adult Human Brain tissue to study Neuroinflammatory and neurodegenerative diseases
- Ryan Mathew, University of Leeds & Leeds Teaching Hospitals NHS Trust, UK: Living Human Brain Tissue in Neuro-Oncology Research
- Cheney Drew, Cardiff University Finance, UK: Ensuring governance, quality and equity of access to researchers - a personal experience
- Sam Booker, Edinburgh University, UK: Knowing your tissue - the importance and value of phenotyping
- Siebzehnrubl Florian, Cardiff University, UK: Why I bother collaborating with academic neurosurgeons
Wednesday 26th April 2023, 09:30 - 11:10 BST
Novel imaging technologies, optical clearing for large organs and data analysis tools
- Cristina Martinez-Gonzalez, University of Edinburgh, UK: Whole-brain light sheet imaging of behaviourally-activated neurons in the rat
- Steven J. West, The Sainsbury Wellcome Centre for Neural Circuits and Behaviour, UK: Automated annotation of histology data with registration to tissue atlases
- Alain Chedotal, Institut de la Vision, Inserm, France: 3D imaging of the developing human nervous system with tissue clearing and light sheet microscopy
- Gail McConnell, University of Strathclyde, UK: Optical mesoscopy with the Mesolens
Other (e.g. history, teaching, outreach etc)
Sunday 23rd April 2023, 12:00 - 14:40 BST
Patient and public involvement in research: Parkinson's and beyond (WORKSHOP). Full information
- Laura Jacobs, Parkinson's UK, London, UK
- Ellen Poliakoff, The University of Manchester, UK
- Carroll Siu, Parkinson's UK Volunteer, UK
- Matthew Sullivan, Parkinson's UK Volunteer, UK
- Heather Mortiboys, University of Sheffield, UK
Monday 24th April 15:30 - 17:10 BST
WORKSHOP: Neuroscience education and teaching
Session convened by the Joint Neurosciences Council
- Nick Kane, Joint Neurosciences Council, UK: (co-chair)
- Linford Fernandes, Leeds Teaching Hospitals, UK: (co-chair)
- Simon Thomson, Ebrain UK: Introduction to workshop
- Joanne Pugh and Danielle Green: Behind the scenes of building an eLearning neuroscience website
- Geraint Fuller, Gloucestershire Hospitals NHS Trust, UK: Teaching and Learning Clinical Neurology: Incorporating neuroscience
- Phil Smith, Cardiff, UK: Assessing neuroscientists and neurologists using single best answer questions
- Amit Batla, University College London, UK: Shaping Ebrain: Applying principles to practice
Tuesday 25th April 2023, 09:30 - 11:10 BST
Making your science communication go further: a workshop from the editors of Inspire the Mind (WORKSHOP). Full information
- Carmine Pariante, King's College London, UK: So, you want to be famous? How to engage media in science communication
- Courtney Worrell, King's College London, UK: The secrets of writing an impactful and informative science blog for a lay audience
- Carolina Estevao, King's College London, UK: Bringing a fresh voice to science podcasting: the experience of “At the back of your mind”
- Clare Liedstrand, University of Westminister, UK: Combatting science denial: How to communicate science in a climate of misinformation
- Amina Begum, University of Westminster, UK: The structure of a blog: a practical exercise
- Ally Jaffee, NHS, UK: The structure of a blog: a practical exercise
- Gargi Mandal, King's College London, UK: Writing about science for different audiences: a practical exercise
Tuesday 25th April 2023, 15:30 - 17:10 BST
The future of publishing in translational neuroscience: (WORKSHOP) Full information
Session convened by the Guarantors of Brain
- Phil Bishop, OUP, UK: Open Access publishing and where we are with Plan S
- Masud Husain, University of Oxford, UK: The view from the Editor’s desk: Publishing in Brain
- Jeff Dalley, University of Cambridge, UK: Publishing in Brain and Neuroscience Advances and registered reports
- Manuela Marescotti, University of Edinburgh, UK: The lack of gender bias in editorial processes at Brain Communications